Istria and Kvarner Bay is the winemaking region located on the North-Western portion of the Croatian Adriatic Coastline, and includes the Istrian peninsula as well as the winemaking region around Rijeka and Opatija, as well as islands Krk, Rab, Cres, Lošinj and Pag. Although quite large and varied with multiple characteristics (soil composition, elevation of the vineyards etc.), the climate of the region is a mild sub-Mediterranean climate typical for the region, with mild and rainy autumns and winters.

The most important white varieties in the region are Malvazija, an indigenous wine variety from Istria and Žlahtina, an indigenous variety from Krk Island. The most common red varieties are Teran, Merlot and Cabernet Sauvignon. Yellow Muscat from the Momjan region, also known as Muškat Momjanski, is a type of dessert wine made in Istria.